Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 5/20 | 0.39 |
| ▸ | BCL6 | P41182 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243115 | 0.97 | CSNK2B (0.42) | CSNK2BBCL6GBA1P2RX3CSNK2A1 | |
| SCHEMBL19512337 | 0.92 | CSNK2B (0.40) | CSNK2BBCL6CSNK2A1GSK3BHIPK2 | |
| SCHEMBL19512336 | 0.92 | CSNK2B (0.40) | CSNK2BBCL6CSNK2A1GSK3BHIPK2 | |
| SCHEMBL15368795 | 0.91 | CSNK2B (0.39) | CSNK2BBCL6GBA1P2RX3CSNK2A1 | |
| SCHEMBL12645424 | 0.90 | CSNK2B (0.37) | CSNK2BBCL6CSNK2A1GSK3BHIPK2 | |
| SCHEMBL14243264 | 0.90 | CSNK2B (0.37) | CSNK2BBCL6CSNK2A1GSK3BHIPK2 | |
| SCHEMBL14242894 | 0.90 | CSNK2B (0.38) | CSNK2BBCL6P2RX3CSNK2A1GSK3B | |
| SCHEMBL14158332 | 0.88 | CSNK2B (0.41) | CSNK2BBCL6CSNK2A1GSK3BMAPT | |
| SCHEMBL2034252 | 0.88 | CSNK2B (0.39) | CSNK2BBCL6CSNK2A1GSK3BHIPK2 | |
| SCHEMBL2034249 | 0.88 | CSNK2B (0.39) | CSNK2BBCL6CSNK2A1GSK3BHIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9303033-B2 | Pyrazolopyrimidines and related heterocycles as CK2 inhibitors | SENHWA BIOSCIENCES, INC. (TW) | 2016-04-05 | — | — | US | disclosed |
| US-8575177-B2 | Pyrazolopyrimidines and related heterocycles as CK2 inhibitors | SENHWA BIOSCIENCES, INC. (TW) | 2013-11-05 | — | — | US | disclosed |
| WO-2012170827-A2 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |