Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.61 |
| ▸ | CNR1 | P21554 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243479 | 1.00 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL18098815 | 1.00 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL20057514 | 0.81 | CNR2 (0.54) | CNR2CNR1 | |
| SCHEMBL20057357 | 0.81 | CNR2 (0.54) | CNR2CNR1 | |
| SCHEMBL20057373 | 0.80 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL20057359 | 0.80 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL15776508 | 0.77 | CNR2 (0.68) | CNR2CNR1 | |
| SCHEMBL14167091 | 0.76 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL14226464 | 0.76 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL14226468 | 0.76 | CNR2 (1.00) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3072886-A1 | PYRIDIN-2-AMIDES USEFUL AS CB2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2016-09-28 | — | — | EP | disclosed |
| WO-2012168350-A1 | PYRIDIN- 2 -AMIDES USEFUL AS CB2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-12-13 | — | — | WO | disclosed |