Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 17/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247728 | 0.93 | PI4KA (0.55) | PI4KAPIK3CGPIK3CAPIK3CD | |
| SCHEMBL30089076 | 0.91 | PI4KA (0.61) | PI4KAPIK3CGPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL14247403 | 0.91 | PI4KA (0.61) | PI4KAPIK3CGPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL29923006 | 0.91 | PI4KA (0.61) | PI4KAPIK3CGPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL14247335 | 0.89 | PI4KA (0.56) | PI4KAPIK3CGPIK3CAPIK3CD | |
| SCHEMBL14317917 | 0.88 | PIK3CG (0.67) | PI4KAPIK3CGPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL14247284 | 0.88 | PIK3CG (0.54) | PI4KAPIK3CGPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL14247396 | 0.86 | PIK3CG (0.48) | PI4KAPIK3CGPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL14305946 | 0.86 | PIK3CG (0.56) | PI4KAPIK3CGPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL14247306 | 0.86 | PIK3CG (0.54) | PI4KAPIK3CGPIK3CAPIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |