Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14252825 | 0.85 | SETD7 (0.47) | SETD7FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL14262776 | 0.85 | SETD7 (0.61) | SETD7FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL12777874 | 0.81 | FNTA (0.50) | SETD7FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL12751049 | 0.79 | FNTA (0.51) | SETD7FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL1473049 | 0.76 | FNTA (0.46) | FNTAFNTB | |
| SCHEMBL14252821 | 0.75 | SETD7 (0.42) | SETD7FNTAFNTBOPRD1KCNH2 | |
| SCHEMBL12751047 | 0.75 | SETD7 (0.42) | SETD7FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL14252952 | 0.74 | SETD7 (0.51) | SETD7FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL14252827 | 0.74 | SETD7 (0.50) | SETD7FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL14252954 | 0.73 | SETD7 (0.47) | SETD7FNTAFNTBOPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348337-B2 | Indole, azaindole and related heterocyclic 4-alkenyl piperidine amides | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-03-25 | — | — | US | disclosed |