Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14083304 | 0.91 | MAPT (0.63) | MAPTLMNAGAAGRM4HDAC6 | |
| SCHEMBL14083302 | 0.87 | GRM4 (0.63) | MAPTLMNAGRM4HDAC6AURKB | |
| SCHEMBL14083382 | 0.87 | MAPT (0.59) | MAPTLMNAGAAGRM4HDAC6 | |
| SCHEMBL14083759 | 0.85 | MAPT (0.63) | MAPTLMNAGAAGRM4HDAC6 | |
| SCHEMBL14083071 | 0.85 | MAPT (0.63) | MAPTLMNAGAAGRM4TRPV1 | |
| SCHEMBL14083101 | 0.85 | MAPT (0.57) | MAPTLMNAGAAGRM4TRPV1 | |
| SCHEMBL14083305 | 0.85 | TP53 (0.61) | MAPTTRPV1SMN1; SMN2 | |
| SCHEMBL14083301 | 0.84 | AURKB (0.57) | MAPTLMNAGRM4TRPV1AURKB | |
| SCHEMBL14083318 | 0.84 | MAPT (0.59) | MAPTLMNAGAATRPV1AURKB | |
| SCHEMBL14083383 | 0.83 | TRPV1 (0.62) | MAPTTRPV1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |