Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.54 |
| ▸ | GHSR | Q92847 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14083349 | 0.92 | TRPV1 (0.52) | TRPV1GHSRNPC1TSHR | |
| SCHEMBL14083585 | 0.88 | MAPT (0.56) | TRPV1GHSRMAPTNPSR1GFER | |
| SCHEMBL14083185 | 0.87 | TRPV1 (0.48) | TRPV1GHSRMAPTNPSR1GFER | |
| SCHEMBL14083352 | 0.86 | TRPV1 (0.61) | TRPV1HTTMEN1KMT2ANPC1 | |
| SCHEMBL14083348 | 0.85 | TRPV1 (0.59) | TRPV1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL14083356 | 0.85 | TRPV1 (0.57) | TRPV1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL14083359 | 0.84 | TRPV1 (0.52) | TRPV1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14083370 | 0.84 | TRPV1 (0.52) | TRPV1MAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL14083358 | 0.84 | TRPV1 (0.71) | TRPV1 | |
| SCHEMBL14083542 | 0.83 | TRPV1 (0.70) | TRPV1MAPTNPSR1GFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |