Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5739701 | 0.78 | ADORA2A (0.60) | ALDH1A1HPGDKMT2AMEN1ADORA2A | |
| SCHEMBL4846236 | 0.76 | AR (0.58) | SMN1; SMN2LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL4846248 | 0.76 | AR (0.58) | SMN1; SMN2LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL13879492 | 0.72 | AR (0.53) | SMN1; SMN2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL11056954 | 0.69 | KMT2A (0.58) | SMN1; SMN2ALDH1A1KDM4EHPGDALOX12 | |
| SCHEMBL5738724 | 0.69 | KDM4E (0.60) | SMN1; SMN2ALDH1A1KDM4EHPGDALOX12 | |
| SCHEMBL9380400 | 0.68 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL4248531 | 0.67 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL5739138 | 0.67 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL11502497 | 0.66 | AR (0.47) | SMN1; SMN2ALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342012-B2 | Inhibitors of αLβ2 mediated cell adhesion | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-03-11 | — | — | US | disclosed |
| US-7342012-B2 | Inhibitors of αLβ2 mediated cell adhesion | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-03-11 | — | — | US | disclosed |