Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.38 |
| ▸ | MYLK | Q15746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12327193 | 0.86 | HPGD (0.45) | HPGDHSD17B10IGF1RSRCAXL | |
| SCHEMBL14255408 | 0.84 | PRKCE (0.44) | HPGDHSD17B10IGF1RSRCAXL | |
| SCHEMBL14255401 | 0.84 | PRKCE (0.44) | HPGDHSD17B10IGF1RSRCAXL | |
| SCHEMBL14255411 | 0.81 | IGF1R (0.41) | HPGDHSD17B10IGF1RSRCAXL | |
| SCHEMBL14255413 | 0.81 | HPGD (0.41) | HPGDHSD17B10IGF1RSRCAXL | |
| SCHEMBL11315118 | 0.80 | HPGD (0.48) | HPGDHSD17B10IGF1RSRCAXL | |
| SCHEMBL14188439 | 0.78 | HPGD (0.41) | HPGDHSD17B10IGF1RSRCAXL | |
| SCHEMBL30435148 | 0.78 | HPGD (0.41) | HPGDHSD17B10IGF1RSRCAXL | |
| SCHEMBL14008505 | 0.78 | HPGD (0.47) | HPGDHSD17B10IGF1RSRCAXL | |
| SCHEMBL14255415 | 0.77 | PRKCE (0.42) | HPGDHSD17B10IGF1RSRCAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338537-B2 | 2-(amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-03-04 | — | — | US | disclosed |