Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.58 |
| ▸ | RARG | P13631 | 10/20 | 0.58 |
| ▸ | RARA | P10276 | 6/20 | 0.58 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.58 |
| ▸ | RXRA | P19793 | 12/20 | 0.39 |
| ▸ | RXRB | P28702 | 10/20 | 0.39 |
| ▸ | RXRG | P48443 | 6/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901695 | 0.83 | RARB (0.59) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9484589 | 0.80 | RARB (0.65) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL10899364 | 0.79 | RARB (0.63) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8522445 | 0.79 | RARB (0.59) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL3300659 | 0.79 | RARB (0.55) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9483828 | 0.79 | RARB (0.63) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8361240 | 0.77 | RARB (0.57) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL2223445 | 0.77 | RARB (0.53) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL3838094 | 0.77 | RARB (0.57) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL2223568 | 0.77 | RARB (0.53) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025965-A2 | RETINOID COMPOUNDS AND THEIR USE | REINNERVATE LIMITED (GB) | 2008-03-06 | — | — | WO | disclosed |