Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8225254 | 0.94 | CYP3A4 (0.52) | CYP3A4 | |
| SCHEMBL13319367 | 0.91 | CYP3A4 (0.51) | CYP3A4 | |
| SCHEMBL13319356 | 0.88 | CYP3A4 (0.49) | CYP3A4 | |
| SCHEMBL8230647 | 0.88 | CYP3A4 (0.51) | CYP3A4 | |
| SCHEMBL13319421 | 0.87 | CYP3A4 (0.51) | CYP3A4 | |
| SCHEMBL14469515 | 0.85 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL13319460 | 0.85 | CYP3A4 (0.49) | CYP3A4 | |
| SCHEMBL14258760 | 0.85 | CYP3A4 (0.51) | CYP3A4 | |
| SCHEMBL13319395 | 0.84 | CYP3A4 (0.48) | CYP3A4 | |
| SCHEMBL14258910 | 0.84 | CYP3A4 (0.46) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499316-B1 | (1-4-PIPERIDINYL)BENZIMIDAZOLE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORP (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |