⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607128 | 1.00 | — | — | |
| SCHEMBL1426215 | 1.00 | TRIM24 (0.38) | — | |
| SCHEMBL1426651 | 1.00 | TRIM24 (0.38) | — | |
| SCHEMBL5961035 | 1.00 | — | — | |
| SCHEMBL1425882 | 1.00 | TRIM24 (0.38) | — | |
| SCHEMBL605008 | 0.95 | — | — | |
| SCHEMBL606915 | 0.80 | — | — | |
| SCHEMBL603869 | 0.80 | — | — | |
| SCHEMBL1053342 | 0.64 | — | — | |
| SCHEMBL567479 | 0.64 | TRIM24 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680267-B2 | Process for producing amide or lactam | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-25 | — | — | US | disclosed |
| US-20110092699-A1 | PROCESS FOR PRODUCING AMIDE OR LACTAM | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2011-04-21 | — | — | US | disclosed |
| EP-2301918-A1 | PROCESS FOR PRODUCING AMIDE OR LACTAM | Daicel Chemical Industries, Ltd. (JP) | 2011-03-30 | — | — | EP | disclosed |
| US-20100029931-A1 | METHOD FOR PRODUCING LACTAM COMPOUND | SHIBAMOTO AKIHIRO | 2010-02-04 | — | — | US | disclosed |