Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14259083 | 0.88 | KMT2A (0.35) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14259006 | 0.88 | MEN1 (0.40) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14258991 | 0.87 | MAPT (0.39) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14258954 | 0.85 | ADORA1 (0.39) | MAPTADORA1PTPN1 | |
| SCHEMBL14259084 | 0.85 | ADORA1 (0.39) | MAPTADORA1PTPN1 | |
| SCHEMBL14259191 | 0.84 | MEN1 (0.35) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14259062 | 0.84 | ADORA1 (0.35) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14258952 | 0.81 | ADORA1 (0.41) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14259095 | 0.80 | ADORA1 (0.42) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16421668 | 0.79 | ADORA1 (0.39) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008027075-A2 | SULFHYDRYL-REACTIVE, WATER SOLUBLE DYES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-03-06 | — | — | WO | disclosed |