Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 19/20 | 0.85 |
| ▸ | GHSR | Q92847 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73721 | 0.92 | MLNR (1.00) | MLNR | |
| SCHEMBL13392189 | 0.85 | MLNR (0.87) | MLNR | |
| SCHEMBL10057876 | 0.85 | MLNR (0.87) | MLNR | |
| SCHEMBL73811 | 0.85 | MLNR (0.87) | MLNR | |
| SCHEMBL10019931 | 0.84 | MLNR (0.85) | MLNRGHSR | |
| SCHEMBL73725 | 0.84 | MLNR (1.00) | MLNR | |
| SCHEMBL75379 | 0.84 | MLNR (0.88) | MLNRGHSR | |
| SCHEMBL75374 | 0.83 | MLNR (1.00) | MLNR | |
| SCHEMBL75339 | 0.83 | MLNR (0.89) | MLNR | |
| SCHEMBL73769 | 0.83 | MLNR (0.83) | MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033328-A2 | MACROCYCLIC ANTAGONISTS OF THE MOTILIN RECEPTOR FOR TREATMENT OF GASTROINTESTINAL DYSMOTILITY DISORDERS | TRANZYME PHARMA, INC. (US) | 2008-03-20 | — | — | WO | disclosed |