Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003826 | 0.72 | CYP1A2 (0.36) | NPSR1CYP2C19 | |
| SCHEMBL9416802 | 0.71 | MAPT (0.41) | MAPTNPSR1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL3926406 | 0.70 | MAPT (0.36) | MAPTNPSR1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL11882807 | 0.69 | NPSR1 (0.33) | MAPTNPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL11383093 | 0.69 | NPSR1 (0.33) | MAPTNPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL11878328 | 0.69 | NPSR1 (0.33) | MAPTNPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL5683465 | 0.69 | MAPT (0.44) | MAPTNPSR1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL759802 | 0.68 | NPSR1 (0.54) | MAPTNPSR1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL3978516 | 0.68 | MAPT (0.42) | MAPTNPSR1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL10885761 | 0.68 | NPSR1 (0.34) | MAPTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008032164-A2 | BENZIMIDAZOLONE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-03-20 | — | — | WO | disclosed |