Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264189 | 0.95 | MAPT (0.69) | MAPTHSD11B1BCL2L1MCL1TLR8 | |
| SCHEMBL12780756 | 0.87 | TLR8 (0.67) | MAPTHSD11B1BCL2L1MCL1TLR8 | |
| SCHEMBL1020760 | 0.85 | MAPT (0.67) | MAPTHSD11B1BCL2L1MCL1TLR8 | |
| SCHEMBL13892442 | 0.84 | MAPT (0.66) | MAPTHSD11B1BCL2L1MCL1TLR8 | |
| SCHEMBL14264195 | 0.82 | MAPT (0.55) | MAPTHSD11B1BCL2L1MCL1TLR8 | |
| SCHEMBL14264193 | 0.82 | TLR8 (0.55) | MAPTHSD11B1BCL2L1MCL1TLR8 | |
| SCHEMBL15760434 | 0.81 | MAPT (0.56) | MAPTHSD11B1BCL2L1MCL1TLR8 | |
| SCHEMBL2628123 | 0.80 | TLR8 (0.56) | MAPTHSD11B1BCL2L1MCL1TLR8 | |
| SCHEMBL15760415 | 0.79 | MAPT (0.53) | MAPTHSD11B1BCL2L1MCL1SMN1; SMN2 | |
| SCHEMBL14264194 | 0.79 | TLR8 (0.55) | MAPTHSD11B1BCL2L1MCL1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070085-A1 | Sulfonated Polymer Comprising Nitrile-Type Hydrophobic Block And Solid Polymer Electrolyte | HONDA MOTOR CO., LTD. (JP) | 2008-03-20 | — | — | US | disclosed |