Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.58 |
| ▸ | PPARA | Q07869 | 16/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107137 | 1.00 | PPARG (0.58) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5100409 | 0.94 | PPARG (0.54) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5107151 | 0.94 | PPARG (0.57) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5101273 | 0.93 | PPARG (0.53) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5107356 | 0.92 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL14265753 | 0.92 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL5107343 | 0.91 | PPARG (0.51) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5107710 | 0.91 | PPARG (0.58) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5101320 | 0.89 | PPARG (0.56) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5101224 | 0.89 | PPARG (0.49) | PPARGPPARALMNAMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348426-B1 | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents | DR. REDDY'S LABORATIES LIMITED (IN) | 2008-03-25 | — | — | US | disclosed |