SCHEMBL14268270

SCHEMBL14268270

CC[C@H](O)COc1ccc(CCCCNC(=N)NC(=O)c2nc(Cl)c(N)nc2N)cc1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCNN1A P37088 17/20 0.60
KCNH2 Q12809 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14268271 1.00 SCNN1A (0.60) SCNN1AKCNH2
SCHEMBL10028716 1.00 SCNN1A (0.60) SCNN1AKCNH2
SCHEMBL12120483 0.92 SCNN1A (0.61) SCNN1A
552-02 Free Base SCHEMBL9913774 0.92 SCNN1A (0.71) SCNN1A
552-02 Free Base SCHEMBL2015162 0.92 SCNN1A (0.71) SCNN1A
552-02 Free Base SCHEMBL9913757 0.92 SCNN1A (0.71) SCNN1A
552-02 Free Base SCHEMBL19348088 0.92 SCNN1A (0.70) SCNN1A
SCHEMBL14551503 0.91 SCNN1A (0.57) SCNN1AKCNH2
SCHEMBL9913771 0.91 SCNN1A (0.57) SCNN1AKCNH2
552-02 Free Base SCHEMBL15092803 0.91 SCNN1A (0.67) SCNN1AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7332496-B2 Broncholdilator agents; hydration of mucous membranes; respiratory system disorders PARION SCIENCES, INC. (US) 2008-02-19 US disclosed