Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.68 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.68 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4374909 | 1.00 | PTGER4 (0.68) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2209602 | 1.00 | PTGER4 (0.68) | PTGER4PTGER3PTGER2 | |
| SCHEMBL13766272 | 0.97 | PTGER4 (0.67) | PTGER4PTGER3PTGER2 | |
| SCHEMBL14307456 | 0.96 | PTGER4 (0.66) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5812669 | 0.94 | PTGER4 (0.76) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6158522 | 0.94 | PTGER4 (0.76) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6166899 | 0.94 | PTGER4 (0.76) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4687934 | 0.89 | PTGER3 (0.55) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4376498 | 0.89 | PTGER4 (0.56) | PTGER4PTGER3PTGER2 | |
| SCHEMBL14030688 | 0.89 | PTGER4 (0.62) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326716-B2 | Treatment of inflammatory bowel disease | ALLERGAN, INC. (US) | 2008-02-05 | — | — | US | disclosed |
| US-7326716-B2 | Treatment of inflammatory bowel disease | ALLERGAN, INC. (US) | 2008-02-05 | — | — | US | disclosed |
| US-7179820-B2 | Piperidinyl prostaglandin E analogs | ALLERGAN, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| US-7179820-B2 | Piperidinyl prostaglandin E analogs | ALLERGAN, INC. (US) | 2007-02-20 | — | — | US | disclosed |