SCHEMBL1427296

SCHEMBL1427296

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCOC(=O)C=Cc1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 14/20 1.00
TTR P02766 4/20 0.70
DPP4 P27487 1/20 0.70
IAPP P10997 1/20 0.62
CYP3A4 P08684 2/20 0.61
ALOX15 P16050 2/20 0.61
ALOX12 P18054 2/20 0.61
MAPK1 P28482 2/20 0.61
HSD17B10 Q99714 2/20 0.61
KDM4E B2RXH2 1/20 0.61
MEN1 O00255 1/20 0.61
AKR1B10 O60218 1/20 0.61
GMNN O75496 1/20 0.61
ALDH1A1 P00352 1/20 0.61
EGFR P00533 1/20 0.61
LMNA P02545 1/20 0.61
ESR1 P03372 1/20 0.61
ERBB2 P04626 1/20 0.61
LCK P06239 1/20 0.61
FYN P06241 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19359050 1.00 APP (1.00) APPTTRDPP4IAPPCYP3A4
SCHEMBL19358970 1.00 APP (1.00) APPTTRDPP4IAPPCYP3A4
SCHEMBL883450 1.00 APP (1.00) APPTTRDPP4IAPPCYP3A4
SCHEMBL3240552 1.00 APP (1.00) APPTTRDPP4IAPPCYP3A4
SCHEMBL19358968 1.00 APP (1.00) APPTTRDPP4IAPPCYP3A4
SCHEMBL19358979 1.00 APP (1.00) APPTTRDPP4IAPPCYP3A4
SCHEMBL16428904 1.00 APP (1.00) APPTTRDPP4IAPPCYP3A4
SCHEMBL19358995 1.00 APP (1.00) APPTTRDPP4IAPPCYP3A4
SCHEMBL1427294 1.00 APP (1.00) APPTTRDPP4IAPPCYP3A4
SCHEMBL16428905 1.00 APP (1.00) APPTTRDPP4IAPPCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2300030-A2 RICE BRAN EXTRACTS AND METHODS OF USE THEREOF Rice Science, Llc (US) 2011-03-30 EP claimed
US-20100015258-A1 Rice Bran Extracts and Methods of Use Thereof HALPERN, BARUCH 2010-01-21 US claimed
WO-2009143065-A2 RICE BRAN EXTRACTS AND METHODS OF USE THEREOF RICE SCIENCE, LLC (US) 2009-11-26 WO claimed
EP-2300030-A2 RICE BRAN EXTRACTS AND METHODS OF USE THEREOF Rice Science, Llc (US) 2011-03-30 EP disclosed
US-20100015258-A1 Rice Bran Extracts and Methods of Use Thereof HALPERN, BARUCH 2010-01-21 US disclosed
WO-2009143065-A2 RICE BRAN EXTRACTS AND METHODS OF USE THEREOF RICE SCIENCE, LLC (US) 2009-11-26 WO disclosed