Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 20/20 | 0.47 |
| ▸ | SRC | P12931 | 12/20 | 0.45 |
| ▸ | SYK | P43405 | 11/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14276231 | 0.95 | GSK3A (0.46) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL14276158 | 0.91 | GSK3A (0.49) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL14276230 | 0.90 | GSK3A (0.45) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL5681284 | 0.89 | GSK3A (0.46) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL14276164 | 0.86 | GSK3A (0.42) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL5681489 | 0.85 | GSK3A (0.52) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL14276228 | 0.85 | GSK3A (0.48) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL14276139 | 0.85 | GSK3A (0.59) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL5115049 | 0.84 | GSK3A (0.45) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL5114424 | 0.84 | GSK3A (0.55) | GSK3ASRCSYKMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335657-B2 | Cytokine inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-7335657-B2 | Cytokine inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2008-02-26 | — | — | US | disclosed |