Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 15/20 | 0.84 |
| ▸ | CHUK | O15111 | 15/20 | 0.84 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NEK1 | Q96PY6 | 5/20 | 0.51 |
| ▸ | CIT | O14578 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13014536 | 0.91 | IKBKB (0.80) | IKBKBCHUKROCK1CYP2C9NEK1 | |
| SCHEMBL3412839 | 0.91 | IKBKB (1.00) | IKBKBCHUKROCK1CYP2C9NEK1 | |
| SCHEMBL3417995 | 0.89 | IKBKB (0.84) | IKBKBCHUKROCK1CYP2C9NEK1 | |
| Trifluoroacetic Acid SCHEMBL3417480 | 0.87 | IKBKB (0.90) | IKBKBCHUKROCK1CYP2C9NEK1 | |
| SCHEMBL3416353 | 0.85 | IKBKB (0.76) | IKBKBCHUKROCK1CYP2C9NEK1 | |
| SCHEMBL3410174 | 0.85 | IKBKB (0.76) | IKBKBCHUKROCK1CYP2C9NEK1 | |
| Trifluoroacetic Acid SCHEMBL3414334 | 0.84 | IKBKB (0.78) | IKBKBCHUKROCK1CYP2C9NEK1 | |
| SCHEMBL3415911 | 0.84 | IKBKB (0.74) | IKBKBCHUKROCK1CYP2C9NEK1 | |
| SCHEMBL3417481 | 0.83 | IKBKB (0.77) | IKBKBCHUKROCK1CYP2C9NEK1 | |
| SCHEMBL13505112 | 0.83 | IKBKB (0.73) | IKBKBCHUKROCK1CYP2C9NEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008034860-A1 | PYRROLO[2, 3-B]PYRIDIN-4-YL-BENZENESULFONAMIDE COMPOUNDS AS IKK2 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2008-03-27 | — | — | WO | disclosed |