Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376223 | 0.72 | — | — | |
| SCHEMBL11341608 | 0.71 | CYP2C19 (0.41) | CYP2C19POLBBLMATM | |
| SCHEMBL10640370 | 0.70 | CYP2C19 (0.44) | CYP2C19POLBBLMATM | |
| SCHEMBL24316274 | 0.70 | CYP2C19 (0.40) | CYP2C19POLBBLMATM | |
| SCHEMBL22551299 | 0.69 | CYP2C19 (0.60) | CYP2C19POLBBLMATM | |
| SCHEMBL10582483 | 0.68 | MAPT (0.47) | CYP2C19POLBBLMATM | |
| SCHEMBL10583033 | 0.68 | CYP2C19 (0.43) | CYP2C19POLBBLMATM | |
| SCHEMBL24317698 | 0.67 | CYP2C19 (0.38) | CYP2C19POLBBLMATM | |
| SCHEMBL7117978 | 0.67 | CYP2C19 (0.41) | CYP2C19POLBBLMATM | |
| SCHEMBL13996416 | 0.67 | CYP2C19 (0.41) | CYP2C19POLBBLMATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |