Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044736 | 0.83 | KDM4E (0.46) | ADH1BADH1CADH1AKDM4E | |
| SCHEMBL4024374 | 0.83 | KDM4E (0.46) | ADH1BADH1CADH1AKDM4E | |
| SCHEMBL7040650 | 0.83 | KDM4E (0.46) | ADH1BADH1CADH1AKDM4E | |
| SCHEMBL7045031 | 0.83 | KDM4E (0.46) | ADH1BADH1CADH1AKDM4E | |
| SCHEMBL7046540 | 0.83 | KDM4E (0.46) | ADH1BADH1CADH1AKDM4E | |
| SCHEMBL7046005 | 0.83 | KDM4E (0.46) | ADH1BADH1CADH1AKDM4E | |
| SCHEMBL6024558 | 0.83 | KDM4E (0.46) | ADH1BADH1CADH1AKDM4E | |
| SCHEMBL7042149 | 0.83 | KDM4E (0.46) | ADH1BADH1CADH1AKDM4E | |
| SCHEMBL29342609 | 0.80 | KDM4E (0.36) | KDM4E | |
| SCHEMBL12112374 | 0.78 | KDM4E (0.52) | ADH1BADH1CADH1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033431-A1 | SPIROCYCLIC AZETIDINONE DERIVATIVES FOR THE TREATMENT OF DISORDERS OF LIPID METABOLISM, PAIN, DIABETES AND OTHER DISORDERS | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |