Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12729681 | 0.93 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL13755665 | 0.89 | MAPK14 (0.87) | MAPK14MAPK11 | |
| SCHEMBL12729679 | 0.86 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL12728825 | 0.85 | MAPK14 (0.85) | MAPK14MAPK11 | |
| SCHEMBL12729678 | 0.84 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL12729670 | 0.84 | MAPK14 (0.84) | MAPK14MAPK11 | |
| SCHEMBL12729674 | 0.83 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL12729682 | 0.83 | MAPK14 (0.87) | MAPK14MAPK11 | |
| SCHEMBL16576239 | 0.82 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL14280411 | 0.81 | MAPK14 (1.00) | MAPK14MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314876-B2 | Aryl ketone pyrrolo-triazine compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314876-B2 | Aryl ketone pyrrolo-triazine compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-01 | — | — | US | disclosed |