Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4891134 | 0.99 | DPP4 (0.45) | DPP4DPP8DPP7DPP9LMNA | |
| SCHEMBL4915189 | 0.92 | DPP4 (0.46) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4906769 | 0.92 | DPP4 (0.46) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8274773 | 0.88 | DPP4 (0.45) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL4918737 | 0.88 | DPP4 (0.44) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL4913099 | 0.88 | DPP4 (0.44) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4891179 | 0.83 | DPP4 (0.47) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4920596 | 0.82 | DPP4 (0.46) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4917651 | 0.82 | DPP4 (0.46) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL14280845 | 0.81 | DPP4 (0.36) | DPP4DPP8DPP9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080009512-A1 | Tetrahydroquinolones and Aza-Analogues Thereof for Use as Dpp-IV Inhibitors in the Treatment of Diabetes | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | US | disclosed |
| US-20080009512-A1 | Tetrahydroquinolones and Aza-Analogues Thereof for Use as Dpp-IV Inhibitors in the Treatment of Diabetes | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009512-A1 | Tetrahydroquinolones and Aza-Analogues Thereof for Use as Dpp-IV Inhibitors in the Treatment of Diabetes | DPP4, DPP8, DPP3 | DPP4 1/4885DPP8 2/4885DPP7 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.