Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.65 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.65 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.65 |
| ▸ | F10 | P00742 | 2/20 | 0.65 |
| ▸ | PLAT | P00750 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228865 | 1.00 | F2 (0.65) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL14281108 | 1.00 | F2 (0.65) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL14281101 | 0.84 | F2 (0.72) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL3243104 | 0.83 | F2 (0.78) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL14281103 | 0.83 | F2 (0.75) | F2PRSS1PRSS2PRSS3F10 | |
| Hydrochloric Acid SCHEMBL4901664 | 0.82 | F2 (0.77) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL3244747 | 0.81 | F2 (0.74) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL4777953 | 0.80 | F2 (0.73) | F2PRSS1PRSS2PRSS3F10 | |
| Hydrochloric Acid SCHEMBL4901668 | 0.80 | F2 (0.72) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL14281115 | 0.79 | F2 (0.91) | F2PRSS1PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021044-A1 | N-[2-[[(DIAMINOMETHYLENE)AMINO]OXY]ETHYL]-3-[(2,2-DIFLUORO-2-PHENYLETHYL)AMINO]-6-METHYL-2-OXO-1(2H)-PYRAZINEACETAMIDE | PATEL MITUL N | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021044-A1 | N-[2-[[(DIAMINOMETHYLENE)AMINO]OXY]ETHYL]-3-[(2,2-DIFLUORO-2-PHENYLETHYL)AMINO]-6-METHYL-2-OXO-1(2H)-PYRAZINEACETAMIDE | DNPEP, SPINT2, PEPD | F2 154/4885PRSS1 18/4885PRSS2 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.