Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527062 | 0.83 | KDM4E (0.67) | ERN1KDM4EPTGS2RAB9ACDK1 | |
| SCHEMBL4466967 | 0.82 | CNR2 (0.60) | ERN1KDM4EPTGS2RAB9ACDK1 | |
| SCHEMBL13469126 | 0.82 | CNR2 (0.60) | ERN1KDM4EPTGS2RAB9ACDK1 | |
| SCHEMBL5470013 | 0.81 | PTPN1 (0.59) | ERN1LCKTRIM24TRIM33 | |
| SCHEMBL5470008 | 0.81 | PTPN1 (0.59) | ERN1LCKTRIM24TRIM33 | |
| SCHEMBL21428442 | 0.79 | ERN1 (0.67) | ERN1KDM4EPTGS2RAB9ALCK | |
| SCHEMBL21428850 | 0.79 | PTGS1 (0.52) | ERN1PTGS2LCK | |
| SCHEMBL21428814 | 0.79 | PTGS1 (0.50) | ERN1PTGS2LCK | |
| SCHEMBL21428820 | 0.79 | ERN1 (0.67) | ERN1PTGS2LCK | |
| SCHEMBL6640901 | 0.79 | KDM4E (0.68) | ERN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058510-A1 | ALTERING LIGNIN AND WOOD DENSITY | ALELLYX S.A. | 2008-03-06 | — | — | US | disclosed |