Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.52 |
| ▸ | TNNI3K | Q59H18 | 5/20 | 0.52 |
| ▸ | PLK4 | O00444 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | ROS1 | P08922 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.52 |
| ▸ | TYK2 | P29597 | 1/20 | 0.52 |
| ▸ | AXL | P30530 | 1/20 | 0.52 |
| ▸ | FRK | P42685 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583862 | 0.90 | KDR (0.55) | KDRMAPK14TNNI3KPLK4AURKA | |
| SCHEMBL14284392 | 0.86 | KDR (0.60) | KDRMAPK14TNNI3KPLK4AURKA | |
| SCHEMBL17706395 | 0.85 | SMN1; SMN2 (0.45) | BRAFMAPTRAB9AGAA | |
| SCHEMBL14284636 | 0.84 | KDR (0.55) | KDRMAPK14TNNI3KPLK4AURKA | |
| SCHEMBL14284697 | 0.82 | TLR8 (0.58) | KDRMAPK14TNNI3KPLK4AURKA | |
| SCHEMBL13849004 | 0.81 | KDR (0.52) | KDRMAPK14TNNI3KPLK4AURKA | |
| SCHEMBL2238803 | 0.81 | KDR (0.52) | KDRMAPK14TNNI3KPLK4AURKA | |
| SCHEMBL5583621 | 0.81 | TLR7 (0.57) | KDRMAPK14TNNI3KPLK4AURKA | |
| SCHEMBL14284578 | 0.81 | KDR (0.51) | KDRMAPK14TNNI3KPLK4AURKA | |
| SCHEMBL4701462 | 0.80 | MAPT (0.52) | KDRBRAFMAPTRAB9AMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |