Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL27617370 | 0.96 | — | — | |
| Glycine SCHEMBL223346 | 0.96 | — | — | |
| Glycine SCHEMBL17224328 | 0.96 | GLRA1 (0.91) | — | |
| Glycine SCHEMBL33937 | 0.96 | — | — | |
| Glycine SCHEMBL445109 | 0.92 | — | — | |
| Glycine SCHEMBL9995854 | 0.92 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL2161266 | 0.92 | — | — | |
| Glycine SCHEMBL28870808 | 0.92 | — | — | |
| Glycine SCHEMBL8627101 | 0.92 | — | — | |
| Glycine SCHEMBL3121142 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166533-A1 | SYNERGISTIC COMPOSITIONS AND METHODS FOR POTENTIATING ANTI-OXIDATIVE ACTIVITY | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZAT (IL) | 2016-06-16 | — | — | US | claimed |
| US-9060959-B2 | Synergistic compositions and method for potentiating anti-oxidative activity | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2015-06-23 | — | — | US | claimed |
| CN-101970008-B | Palatable solid composition comprising antacid and saliva stimulant | BAYER CONSUMER CARE AG | 2013-10-30 | — | — | CN | claimed |
| CN-101970008-A | Palatable solid composition comprising antacid and saliva stimulant | BAYER CONSUMER CARE AG | 2011-02-09 | — | — | CN | claimed |
| EP-2262534-A1 | PALATABLE SOLID COMPOSITION COMPRISING ANTACID AND SALIVA STIMULANT | Bayer Consumer Care AG (CH) | 2010-12-22 | — | — | EP | claimed |
| WO-2009112156-A1 | PALATABLE SOLID COMPOSITION COMPRISING ANTACID AND SALIVA STIMULANT | BAYER CONSUMER CARE AG (CH) | 2009-09-17 | — | — | WO | claimed |
| WO-2009095210-A1 | COMPOSITION COMPRISING AN ANTACID AND A H2-ANTAGONISTS | BAYER CONSUMER CARE AG (CH) | 2009-08-06 | — | — | WO | claimed |
| WO-2009067234-A1 | COMPOSITION AND METHOD FOR TREATMENT OF ORAL INFLAMMATION AND ULCERATION | ZAHRA MOHAMMED (US) | 2009-05-28 | — | — | WO | claimed |
| US-20090130232-A1 | Composition and method for treatment of oral inflammation an ulceration | ZAHRA MOHAMMED | 2009-05-21 | — | — | US | claimed |
| EP-1857102-A1 | Folic acid supplement | Drugtech Corporation (US) | 2007-11-21 | — | — | EP | claimed |
| EP-0600725-B1 | Pharmaceutical compositions containing a guanidinothiazole and antacids | MCNEIL PPC INC (US) | 1997-09-17 | — | — | EP | claimed |
| EP-0578732-B1 | CHEWABLE ANTACID COMPOSITIONS | PROCTER & GAMBLE (US) | 1996-06-19 | — | — | EP | claimed |
| EP-0578768-B1 | INGESTIBLE PHARMACEUTICAL COMPOSITIONS FOR TREATING UPPER GASTROINTESTINAL TRACT DISTRESS | PROCTER & GAMBLE (US) | 1995-09-27 | — | — | EP | claimed |
| EP-0600725-A1 | Pharmaceutical compositions containing a guanidinothiazole and antacids | McNEIL-PPC, INC. (US) | 1994-06-08 | — | — | EP | claimed |
| EP-0578732-A1 | CHEWABLE ANTACID COMPOSITIONS. | PROCTER & GAMBLE (US) | 1994-01-19 | — | — | EP | claimed |
| EP-0578768-A1 | INGESTIBLE PHARMACEUTICAL COMPOSITIONS FOR TREATING UPPER GASTROINTESTINAL TRACT DISTRESS. | PROCTER & GAMBLE (US) | 1994-01-19 | — | — | EP | claimed |
| US-5244670-A | Ingestible pharmaceutical compositions for treating upper gastrointestinal tract distress | THE PROCTER & GAMBLE COMPANY (US) | 1993-09-14 | — | — | US | claimed |
| WO-1992017164-A1 | INGESTIBLE PHARMACEUTICAL COMPOSITIONS FOR TREATING UPPER GASTROINTESTINAL TRACT DISTRESS | THE PROCTER & GAMBLE COMPANY (US) | 1992-10-15 | — | — | WO | claimed |
| WO-1992017161-A1 | CHEWABLE ANTACID COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-10-15 | — | — | WO | claimed |
| US-4937076-A | CHOCOLATE OR HYDROGENATED TALLOW AS COATING AND BINDER; STORAGE STABILITY | COMBE INCORPORATED (US) | 1990-06-26 | — | — | US | claimed |