Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.80 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100700 | 0.94 | HRH3 (0.91) | HRH3 | |
| SCHEMBL6071138 | 0.94 | HRH3 (0.89) | HRH3PSMB1PSMB5 | |
| SCHEMBL5097463 | 0.89 | HRH3 (1.00) | HRH3 | |
| SCHEMBL6070908 | 0.88 | HRH3 (1.00) | HRH3 | |
| Hydrochloric Acid SCHEMBL6071092 | 0.87 | HRH3 (0.98) | HRH3 | |
| SCHEMBL6071411 | 0.86 | HRH3 (1.00) | HRH3 | |
| SCHEMBL5093660 | 0.82 | HRH3 (0.88) | HRH3 | |
| SCHEMBL18033539 | 0.80 | HRH3 (0.58) | HRH3 | |
| SCHEMBL14287756 | 0.80 | HRH3 (0.68) | HRH3 | |
| SCHEMBL5097299 | 0.79 | HRH3 (0.64) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314937-B2 | Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses | ELI LILLY AND COMPANY (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314937-B2 | Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses | ELI LILLY AND COMPANY (US) | 2008-01-01 | — | — | US | disclosed |