Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | COMT | P21964 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13451741 | 0.73 | TYR (0.35) | HDAC4HDAC2HDAC8TYRCOMT | |
| SCHEMBL9915399 | 0.72 | TYR (0.53) | TYRCOMT | |
| SCHEMBL12968456 | 0.72 | COMT (0.44) | HDAC4HDAC2HDAC8TYRCOMT | |
| SCHEMBL12968429 | 0.69 | TYR (0.38) | TYRCOMTAPP | |
| SCHEMBL1686873 | 0.68 | TYR (0.36) | TYRCOMTAPP | |
| SCHEMBL24635878 | 0.68 | TYR (0.37) | HDAC4HDAC2HDAC8TYRCOMT | |
| SCHEMBL11925263 | 0.68 | TYR (0.44) | TYRCOMT | |
| SCHEMBL17191934 | 0.68 | COMT (0.49) | HDAC4HDAC2HDAC8TYRCOMT | |
| SCHEMBL9664988 | 0.67 | COMT (0.40) | TYRCOMT | |
| SCHEMBL24635887 | 0.67 | CYP2C9 (0.37) | HDAC4HDAC2HDAC8TYRCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317101-B2 | Antibacterial cephalosporins | SANDOZ GMBH (AT) | 2008-01-08 | — | — | US | disclosed |