Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755402 | 0.92 | ESR1 (0.35) | ESR1ESR2MAPK1ALDH1A1KDM4E | |
| SCHEMBL13018433 | 0.89 | SMN1; SMN2 (0.49) | ESR1ESR2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL754940 | 0.86 | HPGD (0.37) | ESR1ESR2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17515582 | 0.84 | MAPT (0.33) | MAPK1SMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL13899919 | 0.84 | MAPT (0.33) | MAPK1SMN1; SMN2ALDH1A1KDM4EKMT2A | |
| Ethylene Glycol SCHEMBL607522 | 0.81 | KDM4E (0.47) | ESR1ESR2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3786415 | 0.79 | MAPT (0.47) | MAPK1SMN1; SMN2ALDH1A1KDM4EALOX15 | |
| SCHEMBL1023907 | 0.79 | HPGD (0.41) | ESR1ESR2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12370702 | 0.77 | SMN1; SMN2 (0.46) | ESR1ESR2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL35471 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7316883-B2 | Heat-sensitive lithographic printing plate | FUJILFILM CORPORATION, LTD. (JP) | 2008-01-08 | — | — | US | disclosed |