Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899172 | 1.00 | MC4R (0.41) | MC4RDPP4HDAC8HDAC1P2RX7 | |
| SCHEMBL2899175 | 1.00 | MC4R (0.41) | MC4RDPP4HDAC8HDAC1P2RX7 | |
| SCHEMBL1748779 | 0.92 | DPP4 (0.48) | MC4RDPP4HDAC8HDAC1HDAC3 | |
| SCHEMBL4778870 | 0.92 | DPP4 (0.48) | MC4RDPP4HDAC8HDAC1HDAC3 | |
| SCHEMBL5129579 | 0.92 | DPP4 (0.48) | MC4RDPP4HDAC8HDAC1HDAC3 | |
| SCHEMBL1748778 | 0.92 | DPP4 (0.48) | MC4RDPP4HDAC8HDAC1HDAC3 | |
| SCHEMBL4778879 | 0.92 | DPP4 (0.48) | MC4RDPP4HDAC8HDAC1HDAC3 | |
| SCHEMBL5031635 | 0.91 | MC4R (0.36) | MC4RDPP4FAPDPP8DPP9 | |
| SCHEMBL1748571 | 0.91 | MC4R (0.36) | MC4RDPP4FAPDPP8DPP9 | |
| SCHEMBL1748573 | 0.91 | MC4R (0.36) | MC4RDPP4FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017852-A1 | DIAMINE-CONTAINING, TETRA- SUBSTITUTED PIPERAZINE COMPOUNDS AS MELANOCORTIN RECEPTOR MODULATORS | PALATIN TECHNOLOGIES, INC. (US) | 2008-02-14 | — | — | WO | disclosed |