Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233899 | 0.84 | HCAR2 (0.64) | TP53THRBKMT2ANPSR1L3MBTL1 | |
| SCHEMBL7705757 | 0.83 | HCAR2 (0.59) | TP53THRBKMT2ANPSR1L3MBTL1 | |
| SCHEMBL1259028 | 0.81 | HCAR2 (0.66) | TP53THRBKMT2ANPSR1L3MBTL1 | |
| SCHEMBL21607841 | 0.81 | HCAR2 (0.66) | TP53THRBKMT2ANPSR1L3MBTL1 | |
| SCHEMBL20525148 | 0.81 | KMT2A (0.50) | TP53THRBKMT2ANPSR1L3MBTL1 | |
| SCHEMBL20468132 | 0.81 | HCAR2 (0.53) | TP53THRBKMT2ANPSR1L3MBTL1 | |
| SCHEMBL11093186 | 0.81 | KMT2A (0.50) | TP53THRBKMT2ANPSR1L3MBTL1 | |
| SCHEMBL1665229 | 0.80 | DAO (0.58) | TP53THRBKMT2ANPSR1L3MBTL1 | |
| SCHEMBL20521912 | 0.79 | HCAR2 (0.50) | TP53THRBKMT2ANPSR1L3MBTL1 | |
| SCHEMBL6366232 | 0.79 | HCAR2 (0.68) | TP53THRBKMT2ANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |