Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | TP53 | P04637 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | USP2 | O75604 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14426817 | 0.90 | MAPT (0.70) | MAPTALDH1A1TP53KDM4EUSP2 | |
| SCHEMBL14426815 | 0.86 | MAPT (0.69) | MAPTALDH1A1TP53KDM4EUSP2 | |
| SCHEMBL14426800 | 0.85 | MAPT (0.77) | MAPTALDH1A1TP53KDM4EUSP2 | |
| SCHEMBL14426827 | 0.84 | MAPT (0.62) | MAPTALDH1A1TP53KDM4EUSP2 | |
| SCHEMBL14426814 | 0.82 | MAPT (0.73) | MAPTALDH1A1TP53KDM4EUSP2 | |
| SCHEMBL14426821 | 0.81 | MAPT (0.69) | MAPTALDH1A1TP53KDM4EUSP2 | |
| SCHEMBL14426803 | 0.79 | MAPT (0.64) | MAPTALDH1A1TP53KDM4EUSP2 | |
| SCHEMBL14291661 | 0.79 | MAPT (0.50) | MAPTALDH1A1TP53KDM4EUSP2 | |
| SCHEMBL14426823 | 0.79 | MAPT (0.61) | MAPTALDH1A1TP53KDM4EUSP2 | |
| SCHEMBL14426816 | 0.78 | USP2 (0.58) | MAPTALDH1A1TP53KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024759-A2 | IMMUNOMODULATORY COMPOUNDS THAT TARGET AND INHIBIT THE PY+3 BINDING SITE OF TYROSENE KINASE P56 LCK SH2 DOMAIN | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2008-02-28 | — | — | WO | disclosed |