Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27165131 | 0.87 | CA1 (0.41) | MAPTLMNANPSR1CA1ALDH1A1 | |
| SCHEMBL27204599 | 0.87 | MAPT (0.46) | MAPTLMNANPSR1CA1ALDH1A1 | |
| SCHEMBL27165019 | 0.87 | CA1 (0.41) | MAPTLMNANPSR1CA1ALDH1A1 | |
| SCHEMBL27204598 | 0.87 | MAPT (0.46) | MAPTLMNANPSR1CA1ALDH1A1 | |
| SCHEMBL27165132 | 0.87 | CA1 (0.41) | MAPTLMNANPSR1CA1ALDH1A1 | |
| SCHEMBL27165037 | 0.87 | MAPT (0.46) | MAPTLMNANPSR1CA1ALDH1A1 | |
| SCHEMBL27204578 | 0.86 | MAPT (0.49) | MAPTLMNANPSR1CA1ALDH1A1 | |
| SCHEMBL27204579 | 0.86 | MAPT (0.49) | MAPTLMNANPSR1CA1ALDH1A1 | |
| SCHEMBL14292597 | 0.86 | MAPT (0.49) | MAPTLMNANPSR1CA1ALDH1A1 | |
| SCHEMBL27165036 | 0.86 | MAPT (0.49) | MAPTLMNANPSR1CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022961-A1 | N-HETEROCYCLES SUPPORTED ON POLYMERS THROUGH TRIAZOLE OR TETRAZOLE LINKERS FOR ORGANOCATALYTIC APPLICATIONS | INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2008-02-28 | — | — | WO | disclosed |