Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3416218 | 0.76 | IDO1 (0.38) | GAAALDH1A1LMNASMN1; SMN2CES2 | |
| SCHEMBL548390 | 0.75 | CYP2A6 (0.46) | CYP2A6CHRNA7ACHETDP1STAT3 | |
| SCHEMBL11611731 | 0.75 | CYP2A6 (0.46) | CYP2A6CHRNA7ACHETDP1STAT3 | |
| SCHEMBL15602735 | 0.75 | CYP2A6 (0.46) | CYP2A6CHRNA7ACHETDP1STAT3 | |
| SCHEMBL872965 | 0.73 | CYP2A6 (0.44) | CYP2A6CHRNA7ACHETDP1STAT3 | |
| SCHEMBL4831627 | 0.73 | CYP2A6 (0.44) | CYP2A6CHRNA7ACHETDP1STAT3 | |
| SCHEMBL1532439 | 0.73 | CYP2A6 (0.44) | CYP2A6CHRNA7ACHETDP1STAT3 | |
| SCHEMBL28275831 | 0.73 | CYP2A6 (0.39) | CYP2A6CHRNA7ACHETDP1STAT3 | |
| Isobutane SCHEMBL19460561 | 0.71 | CYP2A6 (0.42) | CYP2A6CHRNA7ACHETDP1STAT3 | |
| SCHEMBL21597319 | 0.71 | CYP2A6 (0.42) | CYP2A6CHRNA7ACHETDP1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024364-A2 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |