Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 18/20 | 0.70 |
| ▸ | MC3R | P41968 | 7/20 | 0.70 |
| ▸ | MC5R | P33032 | 6/20 | 0.70 |
| ▸ | PRCP | P42785 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294538 | 0.97 | MC4R (0.70) | MC4RMC3RMC5RPRCP | |
| SCHEMBL14294720 | 0.92 | MC4R (0.65) | MC4RMC3RMC5RPRCP | |
| SCHEMBL14270801 | 0.90 | MC4R (0.87) | MC4RMC3RMC5R | |
| SCHEMBL14270817 | 0.90 | MC4R (0.87) | MC4RMC3RMC5R | |
| SCHEMBL14294625 | 0.90 | MC4R (0.87) | MC4RMC3RMC5R | |
| SCHEMBL14294626 | 0.89 | MC4R (0.65) | MC4RMC3RMC5RPRCP | |
| SCHEMBL14297484 | 0.89 | MC4R (0.67) | MC4RMC3RMC5RPRCP | |
| SCHEMBL14294695 | 0.89 | MC4R (0.67) | MC4RMC3RMC5RPRCP | |
| SCHEMBL14297479 | 0.87 | MC4R (0.67) | MC4RMC3RMC5RPRCP | |
| SCHEMBL14294548 | 0.87 | MC4R (0.67) | MC4RMC3RMC5RPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051430-A1 | Acylated Piperidine Derivatives as Melanocortin 4-Receptor Agonists | MERCK & CO., INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051430-A1 | Acylated Piperidine Derivatives as Melanocortin 4-Receptor Agonists | MC4R, MC5R, MC3R | MC4R 1/4885MC3R 3/4885MC5R 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.