SCHEMBL14294718

SCHEMBL14294718

CC(=O)N(C(C)C)C(C)c1cc(Cl)c(C)cc1C1CCN(C(=O)C2CN(C(C)(C)C)CC2c2ccc(F)cc2F)CC1

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PRCP P42785 15/20 0.59
▸ MC4R P32245 5/20 0.59
▸ MC3R P41968 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14270808 1.00 PRCP (0.59) PRCPMC4RMC3R
SCHEMBL14294723 0.92 MC4R (0.58) PRCPMC4RMC3R
SCHEMBL14270870 0.92 MC4R (0.58) PRCPMC4RMC3R
SCHEMBL14270863 0.89 PRCP (0.64) PRCPMC4RMC3R
SCHEMBL14270847 0.89 PRCP (0.64) PRCPMC4RMC3R
SCHEMBL14270830 0.89 MC4R (0.52) PRCPMC4RMC3R
SCHEMBL14294693 0.89 MC4R (0.52) PRCPMC4RMC3R
SCHEMBL14270831 0.89 MC4R (0.52) PRCPMC4RMC3R
SCHEMBL14270822 0.89 MC4R (0.52) PRCPMC4RMC3R
SCHEMBL14270809 0.89 MC4R (0.52) PRCPMC4RMC3R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080051430-A1 Acylated Piperidine Derivatives as Melanocortin 4-Receptor Agonists MERCK & CO., INC. 2008-02-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080051430-A1 Acylated Piperidine Derivatives as Melanocortin 4-Receptor Agonists MC4R, MC5R, MC3R PRCP 1527/4885MC4R 1/4885MC3R 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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