Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 17/20 | 0.78 |
| ▸ | RORC | P51449 | 2/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14295107 | 0.93 | NR1H2 (0.77) | NR1H2RORCNR1H3 | |
| SCHEMBL14294990 | 0.92 | NR1H2 (0.79) | NR1H2RORCNR1H3 | |
| SCHEMBL4978012 | 0.88 | NR1H2 (1.00) | NR1H2 | |
| SCHEMBL14295068 | 0.85 | NR1H2 (0.72) | NR1H2RORC | |
| SCHEMBL14294996 | 0.82 | NR1H2 (0.69) | NR1H2RORC | |
| SCHEMBL4612287 | 0.82 | NR1H2 (1.00) | NR1H2 | |
| SCHEMBL4612223 | 0.81 | NR1H2 (1.00) | NR1H2 | |
| SCHEMBL14294925 | 0.79 | NR1H2 (0.72) | NR1H2RORCNR1H3 | |
| SCHEMBL14295062 | 0.79 | NR1H3 (0.60) | NR1H2RORCNR1H3 | |
| SCHEMBL14295063 | 0.78 | NR1H2 (0.61) | NR1H2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326812-B2 | Lipid diseases; metabolism diosrders; antiproliferative agents | AMGEN INC. (US) | 2008-02-05 | — | — | US | disclosed |