Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13974796 | 0.92 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCHRNB2CHRNA4 | |
| SCHEMBL14297376 | 0.87 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCHRNB2CHRNA4 | |
| SCHEMBL21944022 | 0.86 | PPM1B (0.39) | PPM1BPTPN1PPP1CCCHRNB2CHRNA4 | |
| SCHEMBL12732732 | 0.82 | PPM1B (0.43) | PPM1BPTPN1PPP1CCCHRNB2CHRNA4 | |
| SCHEMBL24404660 | 0.80 | PPM1B (0.42) | PPM1BPTPN1PPP1CCCHRNB2CHRNA4 | |
| SCHEMBL21943781 | 0.77 | PPM1B (0.41) | PPM1BPTPN1PPP1CCCHRNB2CHRNA4 | |
| SCHEMBL13517982 | 0.76 | CYP2C19 (0.42) | PPM1BPTPN1PPP1CCCHRNB2CHRNA4 | |
| SCHEMBL29488848 | 0.74 | PPM1B (0.52) | PPM1BPTPN1PPP1CCCHRNB2CHRNA4 | |
| SCHEMBL12732743 | 0.74 | PPM1B (0.52) | PPM1BPTPN1PPP1CCCHRNB2CHRNA4 | |
| SCHEMBL18906445 | 0.74 | MEN1 (0.46) | PPM1BPTPN1PPP1CCCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120321590-A1 | BRIDGED POLYCYCLIC COMPOUNDS | ANADYS PHARMACEUTICALS, INC. (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120321590-A1 | BRIDGED POLYCYCLIC COMPOUNDS | ANADYS PHARMACEUTICALS, INC. (US) | 2012-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120321590-A1 | BRIDGED POLYCYCLIC COMPOUNDS | HCCS, HAVCR2, SLC10A1 | PPM1B 2733/4885PTPN1 4555/4885PPP1CC 3559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.