Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 1/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | ENO1 | P06733 | 1/20 | 0.41 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.36 |
| ▸ | IDH1 | O75874 | 3/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836455 | 0.86 | GALR1 (0.61) | GALR1ENO1SOS1KDM4C | |
| SCHEMBL14300477 | 0.83 | GALR1 (0.49) | GALR1TNK2ENO1RPS6KA6SOS1 | |
| SCHEMBL14302322 | 0.83 | GALR1 (0.47) | GALR1TNK2ENO1RPS6KA6SOS1 | |
| SCHEMBL14300024 | 0.83 | GALR1 (0.47) | GALR1TNK2ENO1RPS6KA6SOS1 | |
| SCHEMBL5552474 | 0.82 | GALR1 (0.41) | GALR1TNK2ENO1RPS6KA6SOS1 | |
| SCHEMBL4829031 | 0.81 | GALR1 (0.42) | GALR1TNK2ENO1RPS6KA6SOS1 | |
| SCHEMBL14300339 | 0.80 | GALR1 (0.44) | GALR1TNK2ENO1RPS6KA6SOS1 | |
| SCHEMBL14300191 | 0.79 | GALR1 (0.46) | GALR1TNK2ENO1RPS6KA6SOS1 | |
| SCHEMBL14302462 | 0.79 | TNK2 (0.64) | GALR1TNK2KCNH3 | |
| SCHEMBL14300025 | 0.79 | GALR1 (0.44) | GALR1TNK2ENO1RPS6KA6SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332488-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |