Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 5/20 | 0.68 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 4/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4339119 | 0.93 | FYN (0.69) | FYNCCNT1CDK9BACE1RET | |
| SCHEMBL102960 | 0.86 | FYN (0.67) | FYNCCNT1CDK9BACE1RET | |
| SCHEMBL14308695 | 0.83 | FYN (0.65) | FYNCCNT1CDK9BACE1RET | |
| SCHEMBL4333481 | 0.83 | FYN (0.68) | FYNCCNT1CDK9BACE1RET | |
| SCHEMBL4340636 | 0.83 | FYN (0.83) | FYNCCNT1CDK9BACE1RET | |
| SCHEMBL14302401 | 0.83 | FYN (0.83) | FYNCCNT1CDK9BACE1RET | |
| SCHEMBL4333443 | 0.82 | FYN (0.74) | FYNCCNT1CDK9BACE1RET | |
| SCHEMBL4344917 | 0.82 | FYN (0.68) | FYNCCNT1CDK9BACE1RET | |
| SCHEMBL4330999 | 0.81 | FYN (0.82) | FYNCCNT1CDK9BACE1RET | |
| SCHEMBL4334679 | 0.81 | FYN (0.65) | FYNCCNT1CDK9BACE1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873157-A1 | Pyrazolopyrimidines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-01-02 | — | — | EP | disclosed |