Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21516152 | 0.85 | TSHR (0.52) | TSHRCYP2C19KDM4EALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL2170417 | 0.77 | CYP2C19 (0.52) | TSHRCYP2D6LMNABLMCYP2C19 | |
| SCHEMBL107090 | 0.74 | CYP2D6 (0.63) | TSHRCYP2D6LMNABLMCYP2C19 | |
| SCHEMBL18510082 | 0.74 | CYP2D6 (0.63) | TSHRCYP2D6LMNABLMCYP2C19 | |
| SCHEMBL68389 | 0.74 | CYP2D6 (0.63) | TSHRCYP2D6LMNABLMCYP2C19 | |
| SCHEMBL805293 | 0.74 | — | — | |
| SCHEMBL8272024 | 0.74 | — | — | |
| SCHEMBL5696888 | 0.74 | — | — | |
| SCHEMBL809387 | 0.74 | — | — | |
| SCHEMBL10174803 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161685-B1 | METHOD FOR REDUCING FLUORESCENCE QUENCHING IN BIOASSAYS | CIS BIO INT (FR) | 2008-01-09 | — | — | EP | disclosed |
| EP-1166119-B1 | HOMOGENEOUS DETECTION AND/OR DETERMINATION METHOD FOR A CHEMICAL OR PHYSICO-CHEMICAL INTERACTION | CIS BIO INT (FR) | 2007-03-14 | — | — | EP | disclosed |