Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 7/20 | 0.82 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.44 |
| ▸ | XIAP | P98170 | 2/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689610 | 0.84 | NOTUM (0.82) | NOTUMHSD17B3XIAPBIRC2 | |
| SCHEMBL17771738 | 0.82 | NOTUM (0.52) | NOTUMSLC6A3 | |
| SCHEMBL1689637 | 0.81 | NOTUM (0.68) | NOTUM | |
| SCHEMBL9910961 | 0.81 | NOTUM (0.80) | NOTUM | |
| SCHEMBL25357646 | 0.80 | NOTUM (0.61) | NOTUM | |
| SCHEMBL1689652 | 0.79 | NOTUM (0.64) | NOTUM | |
| SCHEMBL1689647 | 0.79 | NOTUM (0.64) | NOTUM | |
| SCHEMBL25358257 | 0.77 | NOTUM (0.61) | NOTUMXIAPBIRC2 | |
| SCHEMBL12084217 | 0.76 | NOTUM (0.59) | NOTUMXIAPBIRC2 | |
| SCHEMBL12847641 | 0.76 | NOTUM (0.47) | NOTUMSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880996-A1 | Spiroindolinepiperidine derivatives | Syngenta Limited (GB) | 2008-01-23 | — | — | EP | disclosed |