Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP21 | Q9UK80 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500261 | 0.89 | PTPRB (0.69) | PTPRBMEN1KMT2AMAPTHTT | |
| SCHEMBL500260 | 0.89 | PTPRB (0.69) | PTPRBMEN1KMT2AMAPTHTT | |
| SCHEMBL8522780 | 0.81 | PTPRB (0.46) | PTPRBMEN1KMT2AMAPTHTT | |
| SCHEMBL8556924 | 0.79 | PTPRB (0.46) | PTPRBMEN1KMT2AMAPTHTT | |
| SCHEMBL19894165 | 0.77 | PTPRB (0.44) | PTPRBMEN1KMT2AMAPTHTT | |
| SCHEMBL27772340 | 0.77 | PTPRB (0.49) | PTPRBMEN1KMT2AMAPTHTT | |
| SCHEMBL684358 | 0.76 | MAPT (0.48) | PTPRBMEN1KMT2AMAPTHTT | |
| SCHEMBL500876 | 0.76 | PTPRB (0.45) | PTPRBMEN1KMT2AMAPTHTT | |
| SCHEMBL500877 | 0.76 | PTPRB (0.45) | PTPRBMEN1KMT2AMAPTHTT | |
| SCHEMBL13165657 | 0.76 | PTPRB (0.82) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002570-A2 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |