Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14304063 | 0.83 | SLC6A4 (0.67) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL13109410 | 0.81 | SLC6A4 (0.68) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL2885442 | 0.81 | SLC6A4 (1.00) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL13109367 | 0.79 | SLC6A4 (0.69) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL6152250 | 0.79 | SLC6A4 (0.68) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL13110055 | 0.78 | SLC6A4 (0.88) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL13109362 | 0.77 | SLC6A4 (0.71) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL13109416 | 0.77 | SLC6A4 (0.69) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL13110117 | 0.76 | SLC6A4 (0.87) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL2888724 | 0.76 | SLC6A4 (1.00) | SLC6A4HRH3SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002817-A1 | BUTYL AND BUTYNYL BENZYL AMINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-01-03 | — | — | WO | disclosed |