Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 17/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CPT2 | P23786 | 1/20 | 0.48 |
| ▸ | CPT1A | P50416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14304108 | 0.93 | CCR1 (0.71) | CCR1ALDH1A1CPT2CPT1A | |
| Hydrochloric Acid SCHEMBL4411645 | 0.91 | CCR1 (0.68) | CCR1ALDH1A1CPT2CPT1A | |
| SCHEMBL14313718 | 0.89 | CCR1 (0.68) | CCR1CPT2CPT1A | |
| SCHEMBL14313698 | 0.88 | CCR1 (0.65) | CCR1 | |
| SCHEMBL4271715 | 0.87 | CCR1 (0.63) | CCR1CPT2CPT1A | |
| SCHEMBL14306242 | 0.86 | CCR1 (0.74) | CCR1ALDH1A1 | |
| SCHEMBL3983726 | 0.85 | CCR1 (0.68) | CCR1CPT2CPT1A | |
| SCHEMBL14313687 | 0.85 | CCR1 (0.68) | CCR1CPT2CPT1A | |
| SCHEMBL14305490 | 0.84 | CCR1 (0.54) | CCR1 | |
| SCHEMBL14313691 | 0.83 | CCR1 (0.72) | CCR1CPT2CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011392-A2 | PROLINE UREA CCR1 ANTAGONISTS FOR THE TREATMENT OF AUTOIMMUNE DISEASES OR INFLAMMATION | LIGAND PHARMACUETICALS INCORPORATED (US) | 2008-01-24 | — | — | WO | disclosed |