SCHEMBL14306239

SCHEMBL14306239

CCc1ccc(NC(=O)N2CCC[C@@H]2C(=O)N(C)Cc2ccc(Cl)cc2)cc1

nearest known ligand 0.92

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 17/20 0.92

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14304103 0.92 CCR1 (1.00) CCR1
SCHEMBL14304132 0.91 CCR1 (1.00) CCR1
SCHEMBL14304120 0.89 CCR1 (0.86) CCR1
SCHEMBL2017143 0.88 CCR1 (1.00) CCR1
SCHEMBL18781692 0.88 CCR1 (1.00) CCR1
SCHEMBL14304122 0.88 CCR1 (0.83) CCR1
SCHEMBL14306207 0.86 CCR1 (0.81) CCR1
SCHEMBL18776068 0.86 CCR1 (0.90) CCR1
SCHEMBL14305499 0.86 CCR1 (0.81) CCR1
SCHEMBL14304117 0.85 CCR1 (0.80) CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008011392-A2 PROLINE UREA CCR1 ANTAGONISTS FOR THE TREATMENT OF AUTOIMMUNE DISEASES OR INFLAMMATION LIGAND PHARMACUETICALS INCORPORATED (US) 2008-01-24 WO disclosed