Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 12/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2486523 | 0.86 | CHRM1 (0.58) | CHRM1ALDH1A1HTT | |
| SCHEMBL2486081 | 0.84 | CHRM1 (0.76) | CHRM1ALDH1A1HTTMAPT | |
| SCHEMBL2486292 | 0.81 | CHRM1 (0.58) | CHRM1ALDH1A1HTT | |
| SCHEMBL2881808 | 0.81 | CHRM1 (0.70) | CHRM1ALDH1A1HTTMAPTLMNA | |
| SCHEMBL2486353 | 0.80 | CHRM1 (0.57) | CHRM1ALDH1A1HTTTP53RXFP1 | |
| SCHEMBL2487845 | 0.80 | CHRM1 (0.57) | CHRM1ALDH1A1HTT | |
| SCHEMBL2487841 | 0.78 | CHRM1 (0.55) | CHRM1ALDH1A1HTT | |
| SCHEMBL2487906 | 0.78 | CHRM1 (0.60) | CHRM1ALDH1A1 | |
| SCHEMBL14308113 | 0.78 | CHRM1 (0.56) | CHRM1ALDH1A1HTTMAPTLMNA | |
| SCHEMBL2488977 | 0.78 | CHRM1 (0.55) | CHRM1ALDH1A1MAPTTP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002621-A2 | BENZYL-SUBSTITUTED QUINOLONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK & CO., INC. (US) | 2008-01-03 | — | — | WO | disclosed |